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West Indian Med J ; 62(6): 504-9, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24756735

RESUMO

OBJECTIVE: This study evaluated treatment strategies for head and neck cancers in a predominantly African American population. METHODS: Data were collected utilizing medical records and the tumour registry at the Howard University Hospital. Kaplan-Meier method was used for survival analysis and Cox proportional hazards regression analysis predicted the hazard of death. RESULTS: Analysis revealed that the main treatment strategy was radiation combined with platinum for all stages except stage I. Cetuximab was employed in only 1% of cases. Kaplan-Meier analysis revealed stage II patients had poorer outcome than stage IV while Cox proportional hazard regression analysis (p = 0.4662) showed that stage I had a significantly lower hazard of death than stage IV (HR = 0.314; p = 0.0272). Contributory factors included tobacco and alcohol but body mass index (BMI) was inversely related to hazard of death. CONCLUSIONS: There was no difference in survival using any treatment modality for African Americans.


Assuntos
Negro ou Afro-Americano , Carcinoma de Células Escamosas/etnologia , Carcinoma de Células Escamosas/terapia , Neoplasias de Cabeça e Pescoço/etnologia , Neoplasias de Cabeça e Pescoço/terapia , Neoplasias Laríngeas/etnologia , Neoplasias Faríngeas/etnologia , Idoso , Carcinoma de Células Escamosas/mortalidade , Feminino , Neoplasias de Cabeça e Pescoço/mortalidade , Humanos , Estimativa de Kaplan-Meier , Neoplasias Laríngeas/terapia , Masculino , Pessoa de Meia-Idade , Neoplasias Faríngeas/terapia , Modelos de Riscos Proporcionais , Estudos Retrospectivos , Carcinoma de Células Escamosas de Cabeça e Pescoço
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